We know the Covid virus damages the lining of your blood vessels. We identified age as a contributing factor; with increasing age, the antibody concentration generated was decreased, and the rate of decrease in the neutralizing antibody concentration was rapid (age 3150 years vs. age 1830 years, B = 0.31, 95% CI 0.5 to 0.1; p = 0.009; Table2; Figure2C). A previous study in the journal Blood Advances from 2020 also affirmed this research, adding that people with Type O blood seem to be more protected from Covid. Cytokine levels and lymphocyte subset counts were measured using flow cytometry (Beamcyte-1026; Changzhou Beamdiag Co., Ltd., Changzhou, China). The discovery of Type Os protective effect is crucial to building an understanding of how the virus works. These include: chills fatigue fever headache muscle pain nausea pain at the injection site redness at the. Now, a "Covid arm" is different from a skin reaction that . doi:10.2144/fsoa-2021-0045, 18. In cases of severe adverse events, the investigator contacted the participant, and the intensity of adverse events was graded according to the adverse events severity scale as follows: 1, mild; 2, moderate; 3, severe; or 4, life-threatening. . Please enable it to take advantage of the complete set of features! The pituitary gland in SARS-CoV-2 infections, vaccinations, and post-COVID syndrome. Women and younger adults tend to have more side effects than men or older adults do. "Rh blood type was protective against SARS-CoV-2 infection, especially for those who were O-negative," they wrote. 2021 Oct 11;76:e3286. He had personal struggles during a life-changing year. Acta Neurol Scand. ae0fcc31ae342fd3a1346ebb1f342fcb, "An Rh status seemed protective against SARS-CoV-2 infection," the study authors wrote. Opens in a new tab or window, Share on LinkedIn. The profile of solicited adverse events in this study was consistent with that of a previous study (20). This can begin anywhere from a few minutes to a few hours after the injection. Lustig Y, Sapir E, Regev-Yochay G, Cohen C, Fluss R, Olmer L, et al. The chances of any of these side effects occurring after vaccination differ according to the specific vaccine. Results: Most participants [582/595; 146 male participants, 449 female participants; mean age 35 (2650 years)] rapidly developed neutralizing antibodies after two doses of the vaccine administered 3-weeks apart. Very common side effects in the . For a March study out of the Southern University of Science and Technology in Shenzhen, China, scientists tracked the blood types of nearly 2,200 COVID-19 patients in Chinese hospitals, along with those of about 27,000 individuals who didn't have COVID-19 in the same areas. Table6 Factors associated with IL-6 level after the administration of the Chinese COVID-19 inactivated vaccine. The early response observed 30 days after the second dose showed a boost effect linked to the same manufacturers scheme. Congestion/runny nose. However, in this study, the GMC in participants in the mixed-manufacturer group was lower than that in participants in the same-manufacturer group, which is perhaps due to the fact that vaccines from different manufacturers were still of the same type (both inactivated vaccines, but a protein or attenuated live vaccine). "Reassuring the public that everything is being done . We excluded 14 (2.4%) participants from the regression analysis and mixed model analysis due to missing data: 8 who withdrew their consent, 2 who did not answer age-related questions, 2 who missed a follow-up visit, and 2 who did not provide blood samples (Figure1). In addition, people who are Black, who have died at a disproportionately high rate from Covid, tend to have higher levels of VWF, too. Blood type doesnt affect much in our daily lives. Lancet (2021) 398:12130. This is why some vaccines require a brief observation period after your shot. *Correspondence: Yi Li, liyilebmed@henu.edu.cn, These authors have contributed equally to this work, Advancing the Understanding of Emergence of SARS-CoV-2 Genetic Variants and COVID-19 Vaccine Efficacy: Essential Clinical and Molecular Insights and Breakthroughs, View all B negative red blood cells can be given to both B and AB patients. Therefore, we designed a multicenter, longitudinal, observational study to evaluate the immunogenicity and reactogenicity of a second dose of inactivated vaccine among those who received the two vaccines from different manufacturers. Yet these risks are relative, meaning people with type O blood are not immune to COVID-19. One, for instance, suggests that people with Type A may have a higher risk of catching Covid-19 and of. All rights reserved. Wong MCS, Wong ELY, Huang J, Cheung AWL, Law K, Chong MKC, et al. (EG) Kinetics of interferon (IL)-6 levels according to (E) age, (F) vaccine manufacturer, (G) occupation and (H) interval between doses of vaccination. -, Wiedmann M, Skattr T, StrayPedersen A, et al. Bull Natl Res Cent. "There are two possibilities: You're Type O so you might not contract the virus because it has no landing stripthere's nothing to attach to," Dr. Udden explains. Since both of those types are fairly rare, the Red Cross works hard to . This result indicates that by changing the interval between vaccinations with the inactivated vaccine from the current 38 weeks to 610 weeks (12), vaccinated people can produce higher levels of neutralizing antibody. As of Dec. 24, there were more than 700,000 reports of adverse events . The most frequent of them are headache, GBS, VST, and transverse myelitis. U.S. federal health agencies have recommended pausing the use of Johnson & Johnson's COVID-19 vaccine after six recipients developed a rare disorder involving blood clots, in a fresh setback to . Med Sci Monit (2022) 28:e938532. Even DNA testing company 23andMe tapped their customers and found that among 750,000 people who were diagnosed and hospitalized for Covid (this was prior to vaccines), those with type O were more protected. if( navigator.sendBeacon ) { Si vous souhaitez personnaliser vos choix, cliquez sur Grer les paramtres de confidentialit. It also can be potentially quite large and thus a bit unsettling. Table5 Factors associated with B-lymphocyte count after the administration of the inactivated Chinese COVID-19 vaccine. Bruising for no. Dynamic IgG seropositivity after rollout of CoronaVac and BNT162b2 COVID-19 vaccines in Chile: A sentinel surveillance study. CNN . doi:10.3760/cma.j.cn112147-20200928-01013, 5. The blood type-infection connection is not unique to the coronavirus. Along with its needed effects, sars-cov-2 (covid-19) mrna-1273 vaccine (the active ingredient contained in Moderna COVID-19 Vaccine) may cause some unwanted effects. 2021;2(9):709056. doi:10.3389/fpubh.2021.709056 This can be a sign of anaphylaxis, a severe allergic reaction. That is the most troubling unknown for me." Weighing the odds In contrast, people with blood type O appear to have about a 50 percent reduced risk of severe COVID-19. Kinetics and persistence of the cellular and humoral immune responses to BNT162b2 mRNA vaccine in SARS-CoV-2-naive and -experienced subjects: Impact of booster dose and breakthrough infections. Careers. That year, research in the journal .css-16acfp5{-webkit-text-decoration:underline;text-decoration:underline;text-decoration-thickness:0.125rem;text-decoration-color:#d2232e;text-underline-offset:0.25rem;color:inherit;-webkit-transition:all 0.3s ease-in-out;transition:all 0.3s ease-in-out;}.css-16acfp5:hover{color:#000;text-decoration-color:border-link-body-hover;background-color:yellow;-webkit-transition:all 0.3s ease-in-out;transition:all 0.3s ease-in-out;}PLOS Genetics revealed that people with Type A blood are more likely to have a severe case of Covid-19. However, the incidence of fever, injection site pain, and malaise in the mixed-manufacturer vaccination group was slightly but significantly (p < 0.01) higher (1/143, 0.71%) than in the same-manufacturer vaccination group (1/425, 0.28; Figure2F). Borobia AM, Carcas AJ, Prez-Olmeda M, Castao L, Bertran MJ, Garca-Prez J, et al. Epub 2021 May 25. But both docs agree it shouldnt actually change anyones behavior. SARS-CoV-2 vaccinations may not only be complicated by GBS but also by distal small fibre neuropathy. Common side effects include fatigue and headache. There was no association with blood type and either susceptibility to COVID-19 infection or disease severity in a large cohort study, researchers said. This can result in pain, redness, or swelling at . In conclusion, safety concerns against SARS-CoV-2 vaccines are backed by an increasing number of studies reporting neurological side effects. In addition, we are grateful to our colleagues Wenning Yang, Yafei Chu, Qiong Ma, and Wenbo Xu, who assisted with sample collection. Neurological autoimmune diseases following vaccinations against SARS-CoV-2: a case series. This article is part of Harvard Medical School's continuing coverage of medicine, biomedical research, medical education and policy related to the SARS-CoV-2 pandemic and the disease COVID-19. Conversely, participants aged >50 years had higher levels of reactive IL-6 than those aged 1830 years (B = 1.0, 95% CI 0.61.5; p < 0.001) (Table6; Figure3E). It is observed that severity of infection would be high among B blood group people. Opens in a new tab or window, Visit us on Twitter. 2021;76:e3286. Co-authors disclosed support from Dell Loy Hansen Heart Foundation Heart Institute, Intermountain Research and Medical Foundation, AstraZeneca, PCORnet, GlaxoSmithKline, CareCentra, and LabMe.ai, as well as licensing of intellectual property from Alluceo and CareCentra. Share on Facebook. Use or keep moving your arm. It's more the everyday things: According to Harvard Medical School physician Abraar Karan, the primary side effects of the COVID-19 vaccine are those pesky, flu-like, symptoms you're used. To date, most of the Chinese population has been vaccinated with the inactivated vaccine. Hearst Magazine Media, Inc. All Rights Reserved. Lancet Respir Med (2022) 10:73948. Shutterstock The researchers at St. Michael's Hospital in Toronto, Canada, examined the test results of 225,556 Canadians who had been tested for COVID-19 between Jan. 15 and Jun. Your body then releases von Willebrand factor, or VWF, into your blood so it can fix the damage to the vessel walls. Not everyone gets side effects. Opens in a new tab or window, Visit us on Instagram. People with Type O blood might be slightly more protected from the virus, and people with Type A slightly more vulnerable. Treatment of these side effects is not at variance from similar conditions due to other causes. Opens in a new tab or window, Visit us on YouTube. .css-13y9o4w{display:block;font-family:GraphikBold,GraphikBold-fallback,Helvetica,Arial,Sans-serif;font-weight:bold;margin-bottom:0;margin-top:0;-webkit-text-decoration:none;text-decoration:none;}@media (any-hover: hover){.css-13y9o4w:hover{color:link-hover;}}@media(max-width: 48rem){.css-13y9o4w{font-size:1.05rem;line-height:1.2;margin-bottom:0.25rem;}}@media(min-width: 40.625rem){.css-13y9o4w{font-size:1.28598rem;line-height:1.2;}}@media(min-width: 48rem){.css-13y9o4w{font-size:1.39461rem;line-height:1.2;margin-bottom:0.5rem;}}@media(min-width: 64rem){.css-13y9o4w{font-size:1.23488rem;line-height:1.3;}}This Coffee Shop Provides Free Therapy for Men, How To Stop Poop From Burning After Spicy Food, What to Do When You Hit Your Head Really Hard, 4 Things Every Man Should Know About Testosterone, The Truth About Testosterone and Your Libido, 20 Minutes of Exercise Lowers Hospitalization Risk. doi:10.1128/spectrum.01181-21, 21. That link was established pretty early on in the pandemic and scientists didn't let it go. HHS Vulnerability Disclosure, Help Neutralizing antibody levels were associated with a 33.89% decrease in anti-SARS-CoV-2 spike protein IgG standardized ELISA titers 180 days after the second vaccination (21), similar to our results, that is, a 32.3% decrease in neutralizing antibody levels in the following 180 days. Once a vaccine goes into your arm, your blood flow increases and immune cells rush to the scene. Among 11,000 patients, blood type A was not associated with increased viral positivity (OR 0.97, 95% CI 0.93-1.01, P=0.11), hospitalization (OR 0.89, 95% CI 0.80-0.99, P=0.03) or ICU admission (OR 0.84, 95% CI 0.69-1.02, P=0.08) compared to type O, and neither were there associations with worse outcomes among patients type B or AB, reported Jeffrey Anderson, MD, of the University of Utah School of Medicine in Salt Lake City, and colleagues. (BE) Kinetics of neutralizing antibodies according to (B) vaccination type, (C) age, (D) occupation, and (E) sex.